Hormones & Signal Transduction 5 Sections28 LessonsLifetime
Hormones with Cell Surface Receptors
Signal Transduction by Water Soluble Hormones
Signal Transduction by Water soluble Hormones involves 5 basic steps:
- The Pathway that involves a specific receptor.
- The G Protein – link between 1 & 3.
- Enzyme.
- Second messenger.
- Protein kinase.
Protein Kinases & Protein Phosphatases
Signal transduction is regulated by Protein Kinases and Protein Phosphatases.
Kinases – phosphorylate.
Phosphatases – dephosphorylate.
The Proteins that are involved in the process are mostly Gene Regulatory Proteins such as Transcription Factors and Enzymes.
Once phosphorylated – it must be then dephosphorylated – why ?
Trimeric G Protein Cycle
G Proteins Family & Their Functions
cAMP Mediated Cascade
Signaling by GTP Binding
