What are the Most Important Features of Acromegaly?

The Biochemistry Online – Free Online Lectures for Medical, Dental and Allied Health Sciences students by the Biochemistry Club.


  • Acromegaly is the abnormality that is due to increased secretion of the Growth hormone after the puberty.
  • The usual cause is a macroadenoma.
  • In acromegaly the bones can become thicker and the soft tissues continue to grow.
  • Growth is specially marked in bones of the hands & feet and, in the membranous bones.
  • The membranous bones include cranium, nose, bosses on the forehead, supraorbital ridges, lower jawbone, and portions of the vertebrae.
  • The jaw grows and the teeth are widely spaced.
  • The lower jaw protrudes forward, sometimes as much as half an inch.
  • The forehead slants forward due to the excess development of the supraorbital ridges.
  • The nose increases to as much as twice the normal size.
  • The feet require size 14 or larger shoes and,
  • The fingers become extremely thickened, so that the hands are almost twice normal size.
All these lectures are organized and listed in detail in their proper sections. To view these lessons please visit the Hormones and Signal Transduction Section in Biochemistry II. This can be approached by directly clicking the Biochemistry II button or it can also be approached from the drop down menu in Biochemistry II tab. Once you reach the section click the curriculum tab to view the full list in the section.
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