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Hypothalamic & Pituitary Hormones
Hypothalamus produces 2 types of endocrine factors:
- Hypothalamic neuropeptides
- Hypothalamic releasing factors
1. Hypothalamic Neuropeptides
These are produced by the supraoptic and paraventricular nuclei of the hypothalamus.
These neurohormones are:
- Antidiuretic Hormone (ADH) also known as Vasopressin
* the precursors are long polypeptides
They are synthesized in hypothalamus.
Cleaved into the active molecule, and
Transported to posterior pituitary & stored there.
These are classified as Hormones of Posterior pituitary.
They are released to bloodstream by exocytosis.
2. Hypothalamic Releasing Factors
The releasing factors are neurosecretions synthesized in the hypothalamus and released through the hypothalamic pituitary portal circulation.
They affect the secretion of pituitary tropic hormone.
The Antidiuretic Hormone and Oxytocin are discussed in there appropriate sections. These are the only 2 hormones of the posterior pituitary.