Hypothalamic & Pituitary Hormones – Endocrine control

Free Online Lectures of Biochemistry for Medical, Dental and Allied Health Sciences by Biochemistry Club

Anterior Pituitary

Hypothalamus → Pituitary

1. GnRH → FSH
2. CRH → ACTH
3. TRH → TSH
4. GHRH → GH
5. PIF → Prolactin inhibition

Posterior Pituitary

1. ADH-Antidiuretic Hormone (Vasopressin)
2. Oxytocin

Hypothalamic & Pituitary Hormones

Hypothalamus produces 2 types of endocrine factors:

1. Hypothalamic neuropeptides
2. Hypothalamic releasing factors

1. Hypothalamic Neuropeptides

Produced by the supraoptic and paraventricular nuclei (hypothalamus)

These neurohormones are:

1. Antidiuretic Hormone (ADH)
2. Oxytocin.

 *  the precursors are long polypeptides

They are synthesized in hypothalamus.

Cleaved into the active molecule, and

Transported to posterior pituitary & stored there.

These are classified as Hormones of Posterior pituitary.

They are released to bloodstream by exocytosis.

2. Hypothalamic Releasing Factors

The releasing factors are neurosecretions synthesized in the hypothalamus and released through the hypothalamic pituitary portal circulation.

They affect the secretion of pituitary tropic hormone.

All these lectures are organized and listed in detail in their proper sections. To view these lessons please visit the Hormones & Signal Transduction Section. This can be approached by directly clicking the Biochemistry II button or it can also be approached from the drop down menu in Biochemistry II tab. Once you reach the section click the curriculum tab to view the full list in the section.

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