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Gonadotropins are Glycoprotein Hormones.
- FSH – Follicle Stimulating Hormone
- LH – Luteinizing Hormone, and
- hCG – human Chorionic Gonadotropin
- LH (Luteinizing hormone) & FSH (Follicle stimulating hormone) are released from anterior pituitary
- The placenta produces human Chorionic Gonadotropin (hCG).
- FSH and LH are secreted under the effect of Gonadotropin Releasing Hormone (GnRH).
- Puberty does not set in until the pulsatile secretion of LHRH is started by hypothalamus.
- The fundamental change during puberty is a reduction in hypothalamic inhibition of LHRH release.
FSH (Follicle stimulating hormone)
METABOLIC ROLE OF FSH
- It is synthesized & secreted by gonadotrophes of the Anterior Pituitary.
- FSH regulates the development, growth, pubertal maturation, & reproductive processes of the body.
- The FSH stimulates growth of ovarian follicles in females & spermatogenesis (Sertoli cells) in males.
- The FSH levels are normally low during childhood & in females, high after menopause.
- High FSH levels are an indication of subfertility and/or infertility.
- Diminished secretion of FSH can result …..
FOR DETAILED LECTURE CLICK HORMONES IN BIOCHEMISTRY II TAB, THEN CLICK ON CURRICULUM TAB TO SEE ALL THE LESSONS IN SEQUENCE