FSH (Gonadotropins)

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GONADOTROPINS

Gonadotropins are Glycoprotein Hormones.

These are:

  1. FSH – Follicle Stimulating Hormone
  2. LH – Luteinizing Hormone, and
  3. hCG – human Chorionic Gonadotropin
  • LH (Luteinizing hormone) & FSH (Follicle stimulating hormone) are released from anterior pituitary
  • The placenta produces human Chorionic Gonadotropin (hCG).
  • FSH and LH are secreted under the effect of Gonadotropin Releasing Hormone (GnRH).
  • Puberty does not set in until the pulsatile secretion of LHRH is started by hypothalamus.
  • The fundamental change during puberty is a reduction in hypothalamic inhibition of LHRH release.

FSH (Follicle stimulating hormone)

METABOLIC ROLE OF FSH

  • It is synthesized & secreted by gonadotrophes of the Anterior Pituitary.
  • FSH regulates the development, growth, pubertal maturation, & reproductive processes of the body.
  • The FSH stimulates growth of ovarian follicles in females & spermatogenesis (Sertoli cells) in males.
  • The FSH levels are normally low during childhood & in females, high after menopause.
  • High FSH levels are an indication of subfertility and/or infertility.
  • Diminished secretion of FSH can result …..

FOR DETAILED LECTURE CLICK HORMONES IN BIOCHEMISTRY II TAB, THEN CLICK ON CURRICULUM TAB TO SEE ALL THE LESSONS IN SEQUENCE

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